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Side Effects of SSRIs

Understanding the Side Effects of SSRIs

By Lisa Fritscher, About.com

Updated: February 07, 2009

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

SSRIs, or selective serotonin reuptake inhibitors, are a class of antidepressants often used in the treatment of phobias. In general, SSRIs are considered to have fewer side effects than many other alternatives. Nonetheless, side effects are possible with any medication. Below are some common side effects of SSRIs. If you experience these or any other unusual symptoms, it is important to speak with your doctor as soon as possible.

  • Headache
  • Gastrointestinal distress, such as nausea or diarrhea
  • Restlessness, nervousness or agitation
  • Changes in sleep patterns, such as insomnia or excessive drowsiness
  • Drowsiness
  • Weight gain or loss
  • Sweating
  • Rash
  • Sexual dysfunction
  • Dizziness
  • Strange dreams

Most of the side effects of SSRIs typically occur during the first few weeks of use, as the body learns to adapt to the new medication. Many people find the side effects tolerable, and experience a lessening of symptoms as the body adjusts to the medication. Nevertheless, it is important to keep your doctor informed of your symptoms. Do not discontinue your medication without first seeking your doctor’s approval.

In rare cases, any medication could cause an allergic reaction. Although this is not common with SSRIs, it is important to know the symptoms. The most common symptom is a rash, which could occur on any part of the body. Seek medical help immediately if you experience a rash, trouble breathing, swelling of the face, throat or tongue, a rapid heartbeat or any other unusual symptom.

Of course, like any medication, SSRIs may not be entirely safe for women who are pregnant or may become pregnant. Research has shown that there may be specific risks associated with SSRIs that are taken during pregnancy. Nonetheless, you and your doctor will need to consider the risks versus benefits of each medication and develop an individual solution that is right for you. Discuss the situation with your doctor before becoming pregnant if possible, or as soon as you know that you are pregnant.

Source:

National Institute of Mental Health. Medications: Antidepressant Medications. April 13, 2008. http://www.nimh.nih.gov/health/publications/medications/complete-publication.shtml#pub8

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